TB-500
A name used for synthetic versions of thymosin beta-4, a 43-amino-acid protein found in most human cells, or of its actin-binding fragment.
Level of evidence
Preclinical — cell and animal studiesWhat it is
Thymosin beta-4 is a 43-amino-acid protein that binds actin, a component of the cell skeleton. Products sold as “TB-500” may be the full-length peptide or a short fragment of its actin-binding region: the certificate of analysis (measured mass) tells which one a batch contains.
State of the research
Research on thymosin beta-4 covers cell migration and tissue repair in cell and animal models. Small clinical studies of full-length thymosin beta-4 formulations (for example eye drops) have been reported; no medicine based on it is approved.
Sources
Last reviewed: October 2026
Summaries of published scientific literature, for information and laboratory research only. They do not describe uses of our products, are not medical advice and do not imply that any compound is safe or effective in humans. Our products are not for human or animal consumption.